Dr. Maximilian M. Hielscher

 

Johannes Gutenberg-University Mainz
Department of Chemistry
Duesbergweg 10–14
Room 2.126
55128 Mainz
Phone: +49 6131/39-21614
E-mail: hielscher@uni-mainz.de
2013–2017 Bachelor Studies in Chemistry at Mainz University
2016 Bachelor Thesis in the Waldvogel group at Mainz University
2017–2019 Master Studies in Chemistry at Mainz University
2018 Undergraduate research assistant in the Waldvogel group at Mainz University
2019 Master Thesis in the Waldvogel group at Mainz University
2019-2024 PhD studies in the Waldvogel Group at Mainz University
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Research interests: electroorganic synthesis, anodic C,C cross-coupling reactions, design of experiments
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Publications: T. J. Neubert, M. M. Hielscher, K. Walter, C. M. Schröter, M. Stage, R. R. Rosencrantz, F. Panis, A. Rompel, K. Balasubramanian, S. R. Waldvogel, H. G. Börner, Electrosynthesis of mussel-inspired adhesive polymers as a novel class of transient enzyme stabilizers, Angew. Chem. Int. Ed. 2025. [DOI: 10.1002/anie.202419684].
T. J. Neubert, M. M. Hielscher, K. Walter, C. M. Schröter, M. Stage, R. R. Rosencrantz, F. Panis, A. Rompel, K. Balasubramanian, S. R. Waldvogel, H. G. Börner, Elektrosynthese Muschel-inspirierter Klebstoffpolymere als neue
Klasse transienter Enzymstabilisatoren, Angew. Chem. 2025. [DOI: 10.1002/ange.202419684].
J. Buchholz, E. K. Oehl, M. M. Hielscher, S. L. Kuhn, D. Schollmeyer, S. R. Waldvogel, Electrochemical Dehydrogenative sp2-Coupling Reaction of Naphthols Accessing a Novel Polycyclic Naphthalenone Motif, Org. Lett. 2024. [DOI: 10.1021/acs.orglett.4c03518].

M. M. Hielscher, J. Schneider, A. H. J. Lohmann, S. R. Waldvogel, Automated Optimization of the Synthesis of Alkyl Arenesulfonates in an Undivided Electrochemical Flow Cell, ChemElectroChem 2024, e202400360. [DOI: 10.1002/celc.202400360]

F. Mast, M. M. Hielscher, T. Wirtanen, M. Erichsen, J. Gauss, G. Diezemann, S. R. Waldvogel, The choice of the right supporting electrolyte in electrochemical reductions: a principal component analysis, JACS 2024. [DOI: 10.1021/jacs.4c00910]

M. M. Hielscher, M. Dörr, J. Schneider, S. R. Waldvogel, LABS: Laboratory Automation and Batch Scheduling – A Modular Open Source Python Program for the Control of Automated Electrochemical Synthesis with a Web Interface, Chem. Asian J. 2023, 18, e202300380. [DOI: 10.1002/asia.202300380] (open access)

M. M. Hielscher, E. K. Oehl, B. Gleede, J. Buchholz, S. R. Waldvogel, Optimization Strategies for the Anodic Phenol-Arene Cross-Coupling Reaction, ChemElectroChem, 2021, 8, 3904–3910.
[DOI: 10.1002/celc.202101226 ] (VIP manuscript, open access)

M. Linden, M. M. Hielscher, B. Endrődi, C. Janáky, S. R. Waldvogel, "Electrochemistry in Flow", 2021, Book chapter in “Flow Chemistry”, Volume 2, 31–68. [DOI: 10.1515/9783110693690]

M. Dörr, M. M. Hielscher, J. Proppe, S. R. Waldvogel, Electrosynthetic Screening and Modern Optimization Strategies for Electrosynthesis of Highly Value-added Products, ChemElectroChem., 2021, 8, 2621–2629.
[DOI: 10.1002/celc.202100318]

M. M. Hielscher, B. Gleede, S. R. Waldvogel, Get into Flow: Design of Experiments as Key Technique in the Optimization of Anodic Dehydrogenative C,C Cross-Coupling Reaction of Phenols in Flow Electrolyzers, Electrochim. Acta, 2021, 368, 137420.
[DOI: 10.1016/j.electacta.2020.137420]

M. Vareka, B. Dahms, M. Lang, M. H. Hoang, M. Trobe, H. Weber, M. M. Hielscher, S. R. Waldvogel, R. Breinbauer, Synthesis of a Bcl9 alpha-helix mimetic for inhibition of PPIs by a combination of electrooxidative phenol coupling and Pd-catalyzed cross coupling, Catalysts 2020, 10, 340.
[DOI: 10.3390/catal1003034]

S. B. Beil, P. Franzmann, T. Müller, M. M. Hielscher, T. Prenzel, D. Pollok, N. Beiser, D. Schollmeyer, S. R. Waldvogel, Investigations on Isomerization and Rearrangement of Polycyclic Arenes under Oxidative Conditions - Anodic versus Reagent-mediated Reactions, Electrochim. Acta 2019, 302, 310–315.
[DOI: 10.1016/j.electacta.2019.02.041]